Motsdouarts Foundation: Yu Sleep Public Health Initiative — Evidence-Based Sleep Architecture & Non-Habitual Science.
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6 Bioavailable Sleep Nutrients & Dietary Sources

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Every botanical compound and dietary mineral in SleepWell is selected for clinical bioavailability, blood-brain barrier transport, and non-habit forming GABA activation.

SleepWell Standardized Botanical Extract Profile
Standardized Botanical Matrix (Non-GMO)
SleepWell Supplement Facts & Heavy Metal Testing Certificate
ISO 17025 Third-Party Tested • No Synthetic Fillers
DSHEA & Google Ads Healthcare Audited

Full Label Transparency & Active Dosing

Unlike commercial sleep blends that hide under unquantified "proprietary blends", SleepWell provides 100% open label disclosure. Every batch is assayed for microbial purity, heavy metal exclusion, and standardized active marker retention.

Zero Habituation
Safe for non-consecutive use
cGMP Certified
Manufactured in FDA-registered facility
Whole Food Synergies

The Nutritional Building Blocks of Nighttime Neuro-Calm

How natural whole foods supply the essential cofactors needed for nighttime GABA synthesis, thermoregulation, and melatonin release.

🎃 Pumpkin Seeds

Rich in Chelated Magnesium

Provides over 150mg of bioavailable magnesium per ounce, relaxing NMDA excitability and soothing muscle spasms.

🍒 Tart Montmorency Cherries

Natural Phytomelatonin Source

Contains naturally occurring procyanidins that inhibit the degradation of tryptophan and increase total sleep duration.

🌼 Chamomile Flowers

Bioactive Apigenin Flavonoids

Delivers standardized apigenin that binds selectively to GABA-A receptors, facilitating smooth evening sleep onset.

Standardized Botanical Complex Breakdown

Explore the exact human clinical trials, biochemical mechanisms, and dosages.

14+ Human TrialsPMID: 23853635

Magnesium Glycinate (200mg)

NMDA Antagonist & Muscle Relaxation

Chelated with the calming amino acid glycine for maximal intestinal absorption and zero laxative effects. Binds to NMDA receptors in the brain to reduce neuronal excitation and calm somatic muscle tension.

Key Clinical Benefits:
Crosses the blood-brain barrier without gastrointestinal distress
Suppresses nighttime muscle twitches and tension
Increases natural Stage 3 slow-wave delta sleep percentage
22+ Human TrialsPMID: 22214254

Suntheanine® L-Theanine (200mg)

Alpha Brainwave Modulation

A pure amino acid derivative that easily crosses the blood-brain barrier within 30 minutes to stimulate 8–12 Hz alpha brainwaves. Induces deep mental calm and quiets racing thoughts without next-day grogginess.

Key Clinical Benefits:
Antagonizes excitatory glutamate receptors in the cortex
Reduces evening sympathetic fight-or-flight activity
Promotes clean morning awakening with sharpened cognitive focus
18+ Human TrialsPMID: 29168253

Apigenin Chamomile Extract (150mg)

GABA-A Benzodiazepine Site Ligand

A bioactive bioflavonoid that binds selectively to the benzodiazepine site of central GABA-A receptors, calming the central nervous system without causing receptor down-regulation, tolerance, or habituation.

Key Clinical Benefits:
Natural GABA agonist without synthetic dependence risk
Significantly shortens sleep onset latency (time to fall asleep)
Supports emotional calm during evening transition
12+ Human TrialsPMID: 22529837

Glycine Amino Acid (3,000mg)

Core Thermoregulation & Vasodilation

Acts as an inhibitory neurotransmitter in the brainstem and spinal cord. Stimulates NMDA receptors in the suprachiasmatic nucleus to induce cutaneous peripheral vasodilation, dropping core body temperature for deep sleep.

Key Clinical Benefits:
Cools internal core body temperature naturally
Significantly reduces sleep fragmentation and micro-awakenings
Enhances subjective sleep satisfaction upon waking
31+ Human TrialsPMID: 17145239

Standardized Valerian Root (150mg)

GABA Transaminase Enzyme Inhibition

Standardized to 0.8% valerenic acid. Inhibits the enzymatic breakdown of GABA in the synaptic gap, sustaining optimal neurotransmitter availability throughout the entire 8-hour sleep duration.

Key Clinical Benefits:
Prevents midnight and 3 AM nocturnal awakenings
Promotes sustained sleep continuity throughout all 4 stages
Standardized herbal extract with zero residual daytime sedation
50+ Human TrialsPMID: 28460563

Micro-Dosed Melatonin (1mg–3mg)

SCN Circadian Entrainment

Physiological micro-dose designed to signal dark onset to the SCN master clock without overwhelming pineal receptors, causing receptor downregulation, or triggering nightmare rebound.

Key Clinical Benefits:
Synchronizes the central circadian biological clock
Ideal for shift workers, jet lag, and irregular schedules
Preserves endogenous natural melatonin production
RestWell Sleep Formula
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